Spermidine Synthase
From Proteopedia
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*Ternary complexes of spermidine synthase | *Ternary complexes of spermidine synthase | ||
| - | **[[3c6k]] - hSPS + methylthioadenosine + spermidine<br /> | + | **[[3c6k]], [[4cxm]], [[4uoe]] - hSPS + methylthioadenosine + spermidine<br /> |
**[[3c6m]] - hSPS + methylthioadenosine + spermine<br /> | **[[3c6m]] - hSPS + methylthioadenosine + spermine<br /> | ||
| - | **[[2pt6]], [[3rie]] - PfSPS + inhibitor + methylthioadenosine<br /> | + | **[[2pt6]], [[3rie]], [[4bp3]], [[4bp1]] - PfSPS + inhibitor + methylthioadenosine<br /> |
**[[2pt9]] - PfSPS + inhibitor + SAM derivative<br /> | **[[2pt9]] - PfSPS + inhibitor + SAM derivative<br /> | ||
| + | **[[4cwa]] - PfSPS + inhibitor + ethanol derivative<br /> | ||
| + | **[[4yv0]], [[4yv1]], [[4yv2]], [[4yuv]], [[4yuw]], [[4yux]], [[4yuy]], [[4yuz]] - TcSPS + inhibitor + SAM derivative<br /> | ||
| + | |||
}} | }} | ||
== References == | == References == | ||
Revision as of 13:11, 30 August 2016
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3D structures of spermidine synthase
Updated on 30-August-2016
References
- ↑ Wu H, Min J, Ikeguchi Y, Zeng H, Dong A, Loppnau P, Pegg AE, Plotnikov AN. Structure and mechanism of spermidine synthases. Biochemistry. 2007 Jul 17;46(28):8331-9. Epub 2007 Jun 22. PMID:17585781 doi:http://dx.doi.org/10.1021/bi602498k
- ↑ Schwartz CE, Wang X, Stevenson RE, Pegg AE. Spermine synthase deficiency resulting in X-linked intellectual disability (Snyder-Robinson syndrome). Methods Mol Biol. 2011;720:437-45. doi: 10.1007/978-1-61779-034-8_28. PMID:21318891 doi:http://dx.doi.org/10.1007/978-1-61779-034-8_28
- ↑ Wu H, Min J, Zeng H, McCloskey DE, Ikeguchi Y, Loppnau P, Michael AJ, Pegg AE, Plotnikov AN. Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism. J Biol Chem. 2008 Jun 6;283(23):16135-46. Epub 2008 Mar 26. PMID:18367445 doi:http://dx.doi.org/10.1074/jbc.M710323200
Created with the participation of Lindsey Butler.
