Stathmin

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Line 30: Line 30:
**[[1sa0]] – rSTM + tubulin + GTP + GDP + anti-gout drug <br />
**[[1sa0]] – rSTM + tubulin + GTP + GDP + anti-gout drug <br />
**[[1sa1]], [[1z2b]] – rSTM + tubulin + GTP + GDP + anti-wart drug <br />
**[[1sa1]], [[1z2b]] – rSTM + tubulin + GTP + GDP + anti-wart drug <br />
-
**[[4eb6]] – rSTM (mutant) + tubulin + GTP + GDP + anti-cancer drug <br />
+
**[[4eb6]], [[5j2u]] – rSTM (mutant) + tubulin + GTP + GDP + anti-cancer drug <br />
**[[3du7]] – rSTM + tubulin + GTP + GDP + phomopsine + anti-gout drug <br />
**[[3du7]] – rSTM + tubulin + GTP + GDP + phomopsine + anti-gout drug <br />
**[[3e22]] – rSTM + tubulin + GTP + GDP + soblidotine + anti-gout drug <br />
**[[3e22]] – rSTM + tubulin + GTP + GDP + soblidotine + anti-gout drug <br />
Line 39: Line 39:
**[[4iij]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP <br />
**[[4iij]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP <br />
**[[4ihj]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ADP <br />
**[[4ihj]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ADP <br />
-
**[[4wbn]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + phosphomethylphosphonic acid adenylate <br />
+
**[[5jqg]], [[4wbn]], [[4i55]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ATP derivative <br />
**[[4o2a]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ADP + inhibitor<br />
**[[4o2a]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ADP + inhibitor<br />
-
**[[4i4t]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + zampanolide <br />
 
**[[4i50]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + epothilone <br />
**[[4i50]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + epothilone <br />
-
**[[4o4l]], [[4tuy]], [[4tv8]], [[4yj2]], [[4yj3]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + anti-cancer drugs<br />
+
**[[4o4l]], [[5j2t]], [[5bmv]], [[5la6]], [[5jh7]], [[5jvd]], [[5fnv]], [[5c8y]], [[5ca0]], [[5ca1]], [[5cb4]], [[4yj2]], [[4yj3]], [[4x1i]], [[4x1k]], [[4x1y]], [[4x20]], [[4tuy]], [[4zol]], [[4tv8]], [[4tv9]], [[4o4j]], [[4o4l]], [[5i50]], [[4i4t]], [[4o4i]], [[4o2l]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ATP derivative + anti-cancer drugs<br />
-
**[[4i55]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + phosphomethylphosphonic acid adenylate <br />
+
**[[4o2b]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + ATP derivative + anti-gout drug<br />
-
**[[4o2b]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + phosphomethylphosphonic acid adenylate + anti-gout drug<br />
+
-
**[[4o4h]], [[4o4j]], [[4o4i]] – rSTM + tubulin + tubulin tyrosine ligase + GTP + GDP + phosphomethylphosphonic acid adenylate + anti-cancer drug<br />
+
}}
}}
== References ==
== References ==
<references/>
<references/>

Revision as of 09:20, 1 September 2016

Rat stathmin SLD domain (magenta) complex with tubulin α chain (grey, pink), tubulin β chain (green, yellow), GTP, sulfate and Mg+2 ions (PDB code 3ryf)

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3D Structures of stathmin

Updated on 01-September-2016

References

  1. ↑ Curmi PA, Gavet O, Charbaut E, Ozon S, Lachkar-Colmerauer S, Manceau V, Siavoshian S, Maucuer A, Sobel A. Stathmin and its phosphoprotein family: general properties, biochemical and functional interaction with tubulin. Cell Struct Funct. 1999 Oct;24(5):345-57. PMID:15216892
  2. ↑ Cheon MS, Fountoulakis M, Cairns NJ, Dierssen M, Herkner K, Lubec G. Decreased protein levels of stathmin in adult brains with Down syndrome and Alzheimer's disease. J Neural Transm Suppl. 2001;(61):281-8. PMID:11771751

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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