2j9a
From Proteopedia
(New page: 200px<br /> <applet load="2j9a" size="450" color="white" frame="true" align="right" spinBox="true" caption="2j9a, resolution 1.73Å" /> '''BLLAP IN COMPLEX WI...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2J9A is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with CL, ZN, DMS, AHY and MPD as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J9A OCA]]. | + | 2J9A is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] and [[http://en.wikipedia.org/wiki/Microcystis_sp. Microcystis sp.]] with CL, ZN, DMS, AHY and MPD as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J9A OCA]]. |
==Reference== | ==Reference== | ||
Binding structure of the leucine aminopeptidase inhibitor microginin FR1., Kraft M, Schleberger C, Weckesser J, Schulz GE, FEBS Lett. 2006 Dec 22;580(30):6943-7. Epub 2006 Dec 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17157838 17157838] | Binding structure of the leucine aminopeptidase inhibitor microginin FR1., Kraft M, Schleberger C, Weckesser J, Schulz GE, FEBS Lett. 2006 Dec 22;580(30):6943-7. Epub 2006 Dec 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17157838 17157838] | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
| + | [[Category: Microcystis sp.]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Kraft, M.]] | [[Category: Kraft, M.]] | ||
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[[Category: protease]] | [[Category: protease]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:06:17 2007'' |
Revision as of 09:01, 30 October 2007
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BLLAP IN COMPLEX WITH MICROGININ FR1
Overview
Natural bioactive compounds are of general interest for pharmaceutical, research because they may serve as leads in drug development campaigns., Among them, microginins are linear peptides known to inhibit various, exopeptidases. The crystal structure of microginin FR1 from Microcystis, sp. bound to bovine lens leucine aminopeptidase was established at 1.73, Angstrom resolution. The observed binding structure could be beneficial, for the design of potent aminopeptidase inhibitors.
About this Structure
2J9A is a [Single protein] structure of sequence from [Bos taurus] and [Microcystis sp.] with CL, ZN, DMS, AHY and MPD as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Binding structure of the leucine aminopeptidase inhibitor microginin FR1., Kraft M, Schleberger C, Weckesser J, Schulz GE, FEBS Lett. 2006 Dec 22;580(30):6943-7. Epub 2006 Dec 4. PMID:17157838
Page seeded by OCA on Tue Oct 30 11:06:17 2007
Categories: Bos taurus | Microcystis sp. | Single protein | Kraft, M. | Schleberger, C. | Schulz, G.E. | Weckesser, J. | AHY | CL | DMS | MPD | ZN | Acetylation | Aminopeptidase | Inhibitor complex hydrolase | Leucine aminopeptidase | Metal-binding | Microcystins | Microginin | Protease
