5ko2
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Mouse pgp 34 linker deleted mutant Hg derivative== | |
- | + | <StructureSection load='5ko2' size='340' side='right' caption='[[5ko2]], [[Resolution|resolution]] 3.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5ko2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KO2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |
- | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kpd|5kpd]], [[5koy|5koy]], [[5kpj|5kpj]], [[5kpi|5kpi]]</td></tr> |
+ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ko2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko2 OCA], [http://pdbe.org/5ko2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ko2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ko2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko2 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Xenobiotic-transporting ATPase]] | ||
+ | [[Category: Esser, L]] | ||
[[Category: Xia, D]] | [[Category: Xia, D]] | ||
[[Category: Zhou, F]] | [[Category: Zhou, F]] | ||
- | [[Category: | + | [[Category: Drug transport]] |
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Mercury derivative]] | ||
+ | [[Category: Mouse pgp]] | ||
+ | [[Category: Multidrug resistance]] |
Revision as of 18:35, 10 December 2016
Mouse pgp 34 linker deleted mutant Hg derivative
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