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5t1j
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet== | |
| - | + | <StructureSection load='5t1j' size='340' side='right' caption='[[5t1j]], [[Resolution|resolution]] 2.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5t1j]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T1J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t1j OCA], [http://pdbe.org/5t1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t1j RCSB], [http://www.ebi.ac.uk/pdbsum/5t1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t1j ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TBX21_MOUSE TBX21_MOUSE]] Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Brandt, G S]] | ||
[[Category: Dekker, J]] | [[Category: Dekker, J]] | ||
| + | [[Category: Glimcher, L H]] | ||
[[Category: Hoang, Q]] | [[Category: Hoang, Q]] | ||
| - | [[Category: | + | [[Category: Hwang, E S]] |
| - | + | ||
[[Category: Lazarevic, V]] | [[Category: Lazarevic, V]] | ||
| + | [[Category: Liu, C F]] | ||
| + | [[Category: Naumova, N]] | ||
| + | [[Category: Petsko, G A]] | ||
[[Category: Ringe, D]] | [[Category: Ringe, D]] | ||
| - | [[Category: | + | [[Category: Dna binding]] |
| - | [[Category: | + | [[Category: Dna looping]] |
| - | [[Category: | + | [[Category: Master regulator]] |
| - | [[Category: | + | [[Category: T-bet]] |
| + | [[Category: Tbox]] | ||
| + | [[Category: Tbx21]] | ||
| + | [[Category: Transcription factor]] | ||
| + | [[Category: Transcription-dna complex]] | ||
| + | [[Category: Transcriptional regulation]] | ||
Revision as of 18:50, 26 October 2016
Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet
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