5j9z

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<StructureSection load='5j9z' size='340' side='right' caption='[[5j9z]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='5j9z' size='340' side='right' caption='[[5j9z]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5j9z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J9Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5j9z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J9Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6HJ:(R)-1-(3-(4-AMINO-3-(1-METHYL-1H-INDOL-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL)PIPERIDIN-1-YL)PROP-2-EN-1-ONE'>6HJ</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6HJ:(R)-1-(3-(4-AMINO-3-(1-METHYL-1H-INDOL-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL)PIPERIDIN-1-YL)PROP-2-EN-1-ONE'>6HJ</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EGFR, ERBB, ERBB1, HER1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j9z OCA], [http://pdbe.org/5j9z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j9z RCSB], [http://www.ebi.ac.uk/pdbsum/5j9z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j9z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j9z OCA], [http://pdbe.org/5j9z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j9z RCSB], [http://www.ebi.ac.uk/pdbsum/5j9z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j9z ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 5j9z" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5j9z" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Becker, C]]
[[Category: Becker, C]]

Revision as of 07:12, 21 February 2019

EGFR-T790M in complex with pyrazolopyrimidine inhibitor 1a

5j9z, resolution 2.50Å

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