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5hl1

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<StructureSection load='5hl1' size='340' side='right' caption='[[5hl1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='5hl1' size='340' side='right' caption='[[5hl1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hl1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HL1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hl1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HL1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=63J:2-(PYRIDIN-2-YL)-N-(5-{4-[6-({[3-(TRIFLUOROMETHOXY)PHENYL]ACETYL}AMINO)PYRIDAZIN-3-YL]BUTYL}-1,3,4-THIADIAZOL-2-YL)ACETAMIDE'>63J</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=63J:2-(PYRIDIN-2-YL)-N-(5-{4-[6-({[3-(TRIFLUOROMETHOXY)PHENYL]ACETYL}AMINO)PYRIDAZIN-3-YL]BUTYL}-1,3,4-THIADIAZOL-2-YL)ACETAMIDE'>63J</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fi2|5fi2]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fi2|5fi2]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLS, GLS1, KIAA0838 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hl1 OCA], [http://pdbe.org/5hl1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hl1 RCSB], [http://www.ebi.ac.uk/pdbsum/5hl1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hl1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hl1 OCA], [http://pdbe.org/5hl1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hl1 RCSB], [http://www.ebi.ac.uk/pdbsum/5hl1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hl1 ProSAT]</span></td></tr>
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</StructureSection>
</StructureSection>
[[Category: Glutaminase]]
[[Category: Glutaminase]]
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[[Category: Human]]
[[Category: Cerione, R A]]
[[Category: Cerione, R A]]
[[Category: Huang, Q]]
[[Category: Huang, Q]]
[[Category: Cb-839]]
[[Category: Cb-839]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 17:24, 15 November 2017

Crystal structure of glutaminase C in complex with inhibitor CB-839

5hl1, resolution 2.40Å

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