This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5ltg
From Proteopedia
(Difference between revisions)
m (Protected "5ltg" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Citrate-bound Pichia angusta Atg18== | |
| - | + | <StructureSection load='5ltg' size='340' side='right' caption='[[5ltg]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ltg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_7073 Cbs 7073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LTG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=870730 CBS 7073])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ltg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ltg OCA], [http://pdbe.org/5ltg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ltg RCSB], [http://www.ebi.ac.uk/pdbsum/5ltg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ltg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ATG18_PICAN ATG18_PICAN]] The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cbs 7073]] | ||
| + | [[Category: Kuhnel, K]] | ||
[[Category: Scacioc, A]] | [[Category: Scacioc, A]] | ||
| - | [[Category: | + | [[Category: Lipid binding protein]] |
| + | [[Category: Membrane binding protein]] | ||
Revision as of 14:15, 15 November 2017
Citrate-bound Pichia angusta Atg18
| |||||||||||
