TNF receptor-associated factor

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**[[1f3v]] – hTRAF2 TRAF domain + TRADD N terminal<br />
**[[1f3v]] – hTRAF2 TRAF domain + TRADD N terminal<br />
**[[3m0a]] – hTRAF2 residues 266-329 + cIAP2<br />
**[[3m0a]] – hTRAF2 residues 266-329 + cIAP2<br />
 +
 +
*TRAF3
 +
 +
**[[4ghu]] – TRAF3 TRAF domain residues 376-567 + antiviral-signaling protein peptide - mouse <br />
 +
 +
*TRAF4
 +
 +
**[[4k8u]], [[3zjb]], [[4m4e]] – hTRAF4 TRAF domain residues 281-470 <br />
 +
 +
*TRAF5
 +
 +
**[[4gjh]] – hTRAF5 TRAF domain residues 381-558 <br />
*TRAF6
*TRAF6
Line 44: Line 56:
**[[1lb6]] – hTRAF6 TRAF domain + CD40 antigen peptide<br />
**[[1lb6]] – hTRAF6 TRAF domain + CD40 antigen peptide<br />
**[[3hct]], [[3hcu]] – hTRAF6 RING+zinc finger 1 domains + ubiquitin-conjugating enzyme E2<br />
**[[3hct]], [[3hcu]] – hTRAF6 RING+zinc finger 1 domains + ubiquitin-conjugating enzyme E2<br />
 +
**[[4z8m]] – hTRAF6 TRAF domain + antiviral-signaling protein peptide<br />
}}
}}
== References ==
== References ==
<references/>
<references/>

Revision as of 08:13, 15 September 2016

Human TRAF2 TRAF domain (green) complex with TNFR type 1 associated death domain protein TRADD (grey) (PDB code 1d01)

Drag the structure with the mouse to rotate

3D Structures of TNF receptor-associated factor

Updated on 15-September-2016

References

  1. Bradley JR, Pober JS. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene. 2001 Oct 1;20(44):6482-91. PMID:11607847 doi:http://dx.doi.org/10.1038/sj.onc.1204788
  2. Park YC, Ye H, Hsia C, Segal D, Rich RL, Liou HC, Myszka DG, Wu H. A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction. Cell. 2000 Jun 23;101(7):777-87. PMID:10892748

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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