Penicillin-binding protein
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='2ex6' size=' | + | <StructureSection load='2ex6' size='350' side='right' scene='47/478544/Cv/1' caption='E. coli PBP 4 complex with the antibiotic ampicillin and glycerol [[2ex6]]'> |
== Function == | == Function == | ||
| Line 61: | Line 61: | ||
**[[3beb]], [[3bec]], [[3mzd]], [[3mze]], [[3mzf]] - EcPBP 5 + antibiotic<br /> | **[[3beb]], [[3bec]], [[3mzd]], [[3mze]], [[3mzf]] - EcPBP 5 + antibiotic<br /> | ||
**[[3ita]] - EcPBP 6 + antibiotic<br /> | **[[3ita]] - EcPBP 6 + antibiotic<br /> | ||
| - | **[[3fwl | + | **[[3fwl]] – EcPBP 1B + antibiotic<br /> |
**[[3a3e]], [[3a3f]], [[3a3i]] – HiPBP 4 + antibiotic<br /> | **[[3a3e]], [[3a3f]], [[3a3i]] – HiPBP 4 + antibiotic<br /> | ||
**[[3ocl]], [[3ocn]], [[3pbo]], [[3pbq]], [[3pbr]], [[3pbs]], [[3pbt]], [[4kqo]], [[4kqq]], [[4kqr]], [[4l0l]] – PaPBP 3 + antibiotic<br /> | **[[3ocl]], [[3ocn]], [[3pbo]], [[3pbq]], [[3pbr]], [[3pbs]], [[3pbt]], [[4kqo]], [[4kqq]], [[4kqr]], [[4l0l]] – PaPBP 3 + antibiotic<br /> | ||
Revision as of 07:36, 20 November 2016
| |||||||||||
3D structures of penicillin-binding protein
Updated on 20-November-2016
References
- ↑ Spratt BG. Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. Proc Natl Acad Sci U S A. 1975 Aug;72(8):2999-3003. PMID:1103132
- ↑ Beadle BM, Nicholas RA, Shoichet BK. Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation. Protein Sci. 2001 Jun;10(6):1254-9. PMID:11369864 doi:http://dx.doi.org/10.1110/ps.52001
- ↑ Kishida H, Unzai S, Roper DI, Lloyd A, Park SY, Tame JR. Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics. Biochemistry. 2006 Jan 24;45(3):783-92. PMID:16411754 doi:10.1021/bi051533t
