Transketolase
From Proteopedia
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<StructureSection load='2r8o' size='350' side='right' caption='E. coli transketolase 1 dimer complex with xylulose-5-phosphate-thiamine diphosphate adduct, ethylene glycol and Ca+2 ion (green) (PDB code [[2r8o]]).' scene=''> | <StructureSection load='2r8o' size='350' side='right' caption='E. coli transketolase 1 dimer complex with xylulose-5-phosphate-thiamine diphosphate adduct, ethylene glycol and Ca+2 ion (green) (PDB code [[2r8o]]).' scene=''> | ||
== Function == | == Function == | ||
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**[[1tka]], [[1tkb]], [[1tkc]] – yTKT + TPP analog | **[[1tka]], [[1tkb]], [[1tkc]] – yTKT + TPP analog | ||
- | **[[1gpu]] - yTKT + TPP derivative | + | **[[1gpu]] - yTKT 1 + TPP derivative |
**[[1itz]] - TKT + TPP – maize | **[[1itz]] - TKT + TPP – maize | ||
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**[[1ngs]] - yTKT + TPP + Ca + erythrose-4-P | **[[1ngs]] - yTKT + TPP + Ca + erythrose-4-P | ||
- | **[[2r5n]] – EcTKT + TPP + ribose 5-P<br /> | + | **[[2r5n]] – EcTKT 1 + TPP + ribose 5-P<br /> |
**[[3upt]] - BtTKT + TPP + ribose 5-P<br /> | **[[3upt]] - BtTKT + TPP + ribose 5-P<br /> | ||
**[[2r8o]] - EcTKT 1 + TPP + xylulose 5-P | **[[2r8o]] - EcTKT 1 + TPP + xylulose 5-P | ||
- | **[[2r8p]] - EcTKT + TPP + fructose 6-P<br /> | + | **[[2r8p]] - EcTKT 1 + TPP + fructose 6-P<br /> |
**[[4kxu]] - hTKT + TPP + sorbitol 6-P<br /> | **[[4kxu]] - hTKT + TPP + sorbitol 6-P<br /> | ||
**[[4kxv]], [[4kxw]] - hTKT + TPP + xylitol 5-P<br /> | **[[4kxv]], [[4kxw]] - hTKT + TPP + xylitol 5-P<br /> |
Revision as of 09:15, 21 September 2016
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3D Structures of transketolase
Updated on 21-September-2016
References
- ↑ Verschueren KH, Kingma J, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW. Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry. 1993 Sep 7;32(35):9031-7. PMID:8369276
- ↑ Asztalos P, Parthier C, Golbik R, Kleinschmidt M, Hubner G, Weiss MS, Friedemann R, Wille G, Tittmann K. Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate. Biochemistry. 2007 Oct 30;46(43):12037-52. Epub 2007 Oct 3. PMID:17914867 doi:10.1021/bi700844m