5t6j

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'''Unreleased structure'''
 
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The entry 5t6j is ON HOLD until Paper Publication
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==Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly==
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<StructureSection load='5t6j' size='340' side='right' caption='[[5t6j]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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Authors: Valverde, R., Jenni, S., Dimitrova, Y., Khin, Y., Harrison, S.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5t6j]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T6J FirstGlance]. <br>
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Description: Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t6j OCA], [http://pdbe.org/5t6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t6j RCSB], [http://www.ebi.ac.uk/pdbsum/5t6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t6j ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Khin, Y]]
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== Function ==
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[[Category: Harrison, S.C]]
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[[http://www.uniprot.org/uniprot/SPC24_YEAST SPC24_YEAST]] Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.<ref>PMID:11266451</ref> <ref>PMID:11952896</ref> <ref>PMID:12514103</ref> [[http://www.uniprot.org/uniprot/DSN1_YEAST DSN1_YEAST]] Acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules.<ref>PMID:12455957</ref> <ref>PMID:14633972</ref> [[http://www.uniprot.org/uniprot/SPC25_YEAST SPC25_YEAST]] Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.<ref>PMID:11266451</ref> <ref>PMID:12514103</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Dimitrova, Y]]
[[Category: Dimitrova, Y]]
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[[Category: Harrison, S C]]
[[Category: Jenni, S]]
[[Category: Jenni, S]]
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[[Category: Khin, Y]]
[[Category: Valverde, R]]
[[Category: Valverde, R]]
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[[Category: Cell cycle]]
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[[Category: Chromosome]]
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[[Category: Complex]]
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[[Category: Kinetochore]]
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[[Category: Mind]]
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[[Category: Mis12]]
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[[Category: Mtw1]]
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[[Category: Ndc80]]
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[[Category: Nuf2]]
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[[Category: Segregation]]
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[[Category: Spc24]]
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[[Category: Spc25]]

Revision as of 19:58, 9 December 2016

Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly

5t6j, resolution 1.75Å

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