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5kya
From Proteopedia
(Difference between revisions)
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==Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core== | ==Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core== | ||
| - | <StructureSection load='5kya' size='340' side='right' caption='[[5kya]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='5kya' size='340' side='right'caption='[[5kya]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5kya]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KYA OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5kya]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KYA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KYA FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6Y4:[2-[(6~{R})-2-(3-METHYLSULFONYLPHENYL)-6-PROPAN-2-YL-4,6-DIHYDROPYRROLO[3,4-C]PYRAZOL-5-YL]-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]METHANOL'>6Y4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6Y4:[2-[(6~{R})-2-(3-METHYLSULFONYLPHENYL)-6-PROPAN-2-YL-4,6-DIHYDROPYRROLO[3,4-C]PYRAZOL-5-YL]-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]METHANOL'>6Y4</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i4v|5i4v]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i4v|5i4v]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kya OCA], [http://pdbe.org/5kya PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kya RCSB], [http://www.ebi.ac.uk/pdbsum/5kya PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kya ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5kya" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5kya" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Liver X receptor|Liver X receptor]] | ||
| + | *[[Retinoid X receptor 3D structures|Retinoid X receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Chen, G]] | [[Category: Chen, G]] | ||
[[Category: McKeever, B M]] | [[Category: McKeever, B M]] | ||
Revision as of 06:37, 5 August 2020
Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core
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