This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Transthyretin
From Proteopedia
(Difference between revisions)
| Line 18: | Line 18: | ||
*Transthyretin | *Transthyretin | ||
| - | **[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]], [[4pvl]], [[4pvn]] – hTTR – human<br /> | + | **[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]], [[4pvl]], [[4pvn]], [[5k1j]], [[5k1n]], [[5cn3]], [[5cnh]], [[5dwp]], [[4tlt]] – hTTR – human<br /> |
**[[3u2j]], [[4pvm]] – hTTR - neutron<br /> | **[[3u2j]], [[4pvm]] – hTTR - neutron<br /> | ||
**[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant) | **[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant) | ||
| Line 24: | Line 24: | ||
**[[1ttr]] – hTTR (cardiomyapatic mutant) | **[[1ttr]] – hTTR (cardiomyapatic mutant) | ||
| - | **[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]], [[4pwe]] – hTTR (mutant) | + | **[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]], [[4pwe]], [[5dej]], [[5clx]], [[5clx]], [[5clz]], [[5cm1]], [[4tlu]], [[4tnf]], [[4tng]], [[4tkw]], [[4tl4]], [[4tl5]], [[4tlk]], [[4tls]], [[4tm9]], [[4tne]] – hTTR (mutant) |
**[[1tfp]] – TTR – chicken | **[[1tfp]] – TTR – chicken | ||
| Line 46: | Line 46: | ||
**[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br /> | **[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br /> | ||
**[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br /> | **[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br /> | ||
| - | **[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]] – hTTR + inhibitor | + | **[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]], [[5e23]], [[5e4a]], [[5e4o]], [[5ezp]], [[5ayt]], [[4ydm]], [[4ydn]], [[4tq8]], [[4tqh]], [[4tqi]], [[4tqp]] – hTTR + inhibitor |
| - | + | **[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]], [[5hjg]] – hTTR + phenol derivative<br /> | |
| - | **[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]] – hTTR + phenol derivative<br /> | + | |
**[[4l1s]] - hTTR + benzamide derivative<br /> | **[[4l1s]] - hTTR + benzamide derivative<br /> | ||
**[[4l1t]] - hTTR + benzoate derivative<br /> | **[[4l1t]] - hTTR + benzoate derivative<br /> | ||
| Line 55: | Line 54: | ||
**[[2b14]], [[2b16]] – hTTR (mutant) + phenol derivative | **[[2b14]], [[2b16]] – hTTR (mutant) + phenol derivative | ||
| - | **[[3kgt]], [[3kgu]] – hTTR (mutant) + genistein | + | **[[3kgt]], [[3kgu]], [[5akv]] – hTTR (mutant) + genistein derivative |
**[[3ng5]] – hTTR (mutant) + epigallocatechin gallate | **[[3ng5]] – hTTR (mutant) + epigallocatechin gallate | ||
| Line 77: | Line 76: | ||
**[[4hjs]], [[4hjt]], [[4hju]] – hTTR + covalent kinetic stabilizer<br /> | **[[4hjs]], [[4hjt]], [[4hju]] – hTTR + covalent kinetic stabilizer<br /> | ||
**[[4pmf]] - hTTR + curcumin<br /> | **[[4pmf]] - hTTR + curcumin<br /> | ||
| - | **[[4qxv]] - hTTR + luteolin<br /> | + | **[[4qxv]], [[5en3]], [[5ihh]] - hTTR + luteolin<br /> |
**[[4qya]] - hTTR (mutant) + luteolin<br /> | **[[4qya]] - hTTR (mutant) + luteolin<br /> | ||
**[[4pwf]] - hTTR (mutant) + ferulic esterase<br /> | **[[4pwf]] - hTTR (mutant) + ferulic esterase<br /> | ||
| Line 83: | Line 82: | ||
**[[4pwi]] - hTTR (mutant) + rosamariic acid<br /> | **[[4pwi]] - hTTR (mutant) + rosamariic acid<br /> | ||
**[[4pwj]], [[4pwk]] - hTTR (mutant) + propolis<br /> | **[[4pwj]], [[4pwk]] - hTTR (mutant) + propolis<br /> | ||
| + | **[[4d7b]] - hTTR + tocalpone<br /> | ||
| + | **[[5a6i]] - hTTR (mutant) + tocalpone<br /> | ||
| + | **[[5aks]], [[5akt]], [[5al0]]- hTTR + resveratrol<br /> | ||
| + | **[[5al8]] - hTTR + daidzein glucuronide<br /> | ||
| + | **[[4y9b]], [[4y9c]], [[4y9e]], [[4y9f]], [[4y9g]] - hTTR (mutant) + mangostin<br /> | ||
| + | **[[4wnj]] - hTTR + quercetin<br /> | ||
| + | **[[4wns]] - hTTR + pterostilbene<br /> | ||
| + | **[[4wo0]] - hTTR + apigenin<br /> | ||
| + | **[[5boj]] - hTTR + gemfibrozil<br /> | ||
*TTR ternary complexes | *TTR ternary complexes | ||
**[[4pme]] - hTTR + ferulic acid + curcumin<br /> | **[[4pme]] - hTTR + ferulic acid + curcumin<br /> | ||
| + | **[[5cr1]]- hTTR + resveratrol + T4<br /> | ||
*Transthyretin complexes with retinol-binding protein | *Transthyretin complexes with retinol-binding protein | ||
Revision as of 08:42, 22 September 2016
| |||||||||||
3D structures of transthyretin
Updated on 22-September-2016
References
- ↑ Robbins J. Transthyretin from discovery to now. Clin Chem Lab Med. 2002 Dec;40(12):1183-90. PMID:12553418 doi:http://dx.doi.org/10.1515/CCLM.2002.208
- ↑ Saraiva MJ. Transthyretin mutations in health and disease. Hum Mutat. 1995;5(3):191-6. PMID:7599630 doi:http://dx.doi.org/10.1002/humu.1380050302
- ↑ Wojtczak A, Luft J, Cody V. Mechanism of molecular recognition. Structural aspects of 3,3'-diiodo-L-thyronine binding to human serum transthyretin. J Biol Chem. 1992 Jan 5;267(1):353-7. PMID:1730601
