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Trypanothione reductase
From Proteopedia
(Difference between revisions)
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**[[1gxf]] - TcTTR + inhibitor<br /> | **[[1gxf]] - TcTTR + inhibitor<br /> | ||
**[[2wba]], [[2wov]] - TbTTR + NADPH <br /> | **[[2wba]], [[2wov]] - TbTTR + NADPH <br /> | ||
| - | **[[2wp5]], [[2wp6]], [[2wpc]], [[2wpe]], [[2wpf]], [[4nev]] - TbTTR + inhibitor<br /> | + | **[[2wp5]], [[2wp6]], [[2wpc]], [[2wpe]], [[2wpf]], [[4nev]], [[4new]] - TbTTR + inhibitor<br /> |
*Trypanothione reductase ternary complex | *Trypanothione reductase ternary complex | ||
Revision as of 06:34, 27 September 2016
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3D structures of trypanothione reductase
Updated on 27-September-2016
References
- ↑ Rivarola HW, Paglini-Oliva PA. Trypanosoma cruzi trypanothione reductase inhibitors: phenothiazines and related compounds modify experimental Chagas' disease evolution. Curr Drug Targets Cardiovasc Haematol Disord. 2002 Jun;2(1):43-52. PMID:12769656
- ↑ Baiocco P, Poce G, Alfonso S, Cocozza M, Porretta GC, Colotti G, Biava M, Moraca F, Botta M, Yardley V, Fiorillo A, Lantella A, Malatesta F, Ilari A. Inhibition of Leishmania infantum Trypanothione Reductase by Azole-Based Compounds: a Comparative Analysis with Its Physiological Substrate by X-ray Crystallography. ChemMedChem. 2013 Jun 3. doi: 10.1002/cmdc.201300176. PMID:23733388 doi:10.1002/cmdc.201300176
