5gu7

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'''Unreleased structure'''
 
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The entry 5gu7 is ON HOLD until Paper Publication
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==Crystal Structure of human ERp44 form II==
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<StructureSection load='5gu7' size='340' side='right' caption='[[5gu7]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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Authors: Watanabe, S., Inaba, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5gu7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GU7 FirstGlance]. <br>
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Description: Crystal Structure of human ERp44 form II
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gu6|5gu6]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu7 OCA], [http://pdbe.org/5gu7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gu7 RCSB], [http://www.ebi.ac.uk/pdbsum/5gu7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ERP44_HUMAN ERP44_HUMAN]] Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.<ref>PMID:11847130</ref> <ref>PMID:14517240</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Inaba, K]]
[[Category: Inaba, K]]
[[Category: Watanabe, S]]
[[Category: Watanabe, S]]
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[[Category: Chaperone]]
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[[Category: Quality control]]

Revision as of 11:41, 12 April 2017

Crystal Structure of human ERp44 form II

5gu7, resolution 2.05Å

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