We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

5lxi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5lxi" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5lxi is ON HOLD
+
==GABARAP-L1 ATG4B LIR Complex==
-
 
+
<StructureSection load='5lxi' size='340' side='right' caption='[[5lxi]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
-
Authors: Mouilleron, S., Skytte Rasmussen, M., Kumar Shrestha, B., Wirth, M., Bowitz Larsen, K., Abudu Princely, Y., Sjottem, E., Tooze, S., Lamark, T., Johansen, T., Lee, R.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5lxi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LXI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LXI FirstGlance]. <br>
-
Description: GABARAP-L1 ATG4B LIR Complex
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lxi OCA], [http://pdbe.org/5lxi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lxi RCSB], [http://www.ebi.ac.uk/pdbsum/5lxi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lxi ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/GBRL1_HUMAN GBRL1_HUMAN]] Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles.<ref>PMID:16431922</ref> <ref>PMID:20404487</ref> [[http://www.uniprot.org/uniprot/ATG4B_HUMAN ATG4B_HUMAN]] Cysteine protease required for autophagy, which cleaves the C-terminal part of MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Also mediates the lipid deconjugation required for target recycling.<ref>PMID:15169837</ref> <ref>PMID:19322194</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Johansen, T]]
[[Category: Lamark, T]]
[[Category: Lamark, T]]
-
[[Category: Skytte Rasmussen, M]]
+
[[Category: Larsen, K Bowitz]]
-
[[Category: Abudu Princely, Y]]
+
[[Category: Lee, R]]
-
[[Category: Bowitz Larsen, K]]
+
-
[[Category: Kumar Shrestha, B]]
+
[[Category: Mouilleron, S]]
[[Category: Mouilleron, S]]
-
[[Category: Wirth, M]]
+
[[Category: Princely, Y Abudu]]
-
[[Category: Lee, R]]
+
[[Category: Rasmussen, M Skytte]]
-
[[Category: Johansen, T]]
+
[[Category: Shrestha, B Kumar]]
[[Category: Sjottem, E]]
[[Category: Sjottem, E]]
[[Category: Tooze, S]]
[[Category: Tooze, S]]
 +
[[Category: Wirth, M]]
 +
[[Category: Atg8]]
 +
[[Category: Gabarap]]
 +
[[Category: Lc3]]
 +
[[Category: Lir]]
 +
[[Category: Signaling protein]]

Revision as of 09:26, 10 March 2017

GABARAP-L1 ATG4B LIR Complex

5lxi, resolution 1.44Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5lxi"
Personal tools