1pcf
From Proteopedia
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'''HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN''' | '''HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN''' | ||
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[[Category: Brandsen, J.]] | [[Category: Brandsen, J.]] | ||
[[Category: Gros, P.]] | [[Category: Gros, P.]] | ||
- | [[Category: | + | [[Category: Nuclear protein]] |
- | [[Category: | + | [[Category: Ssdna binding]] |
- | [[Category: | + | [[Category: Transcription]] |
- | [[Category: | + | [[Category: Transcriptional co-activator]] |
- | [[Category: | + | [[Category: Transcriptional cofactor]] |
- | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:56:01 2008'' | |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 01:56, 3 May 2008
HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN
Overview
The crystal structure of human replication and transcription cofactor PC4CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DNA at promoters or origins of replication.
About this Structure
1PCF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site., Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P, Nat Struct Biol. 1997 Nov;4(11):900-3. PMID:9360603 Page seeded by OCA on Sat May 3 04:56:01 2008