1pdg

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[[Image:1pdg.jpg|left|200px]]
[[Image:1pdg.jpg|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_1pdg", creates the "Structure Box" on the page.
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{{STRUCTURE_1pdg| PDB=1pdg | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pdg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pdg OCA], [http://www.ebi.ac.uk/pdbsum/1pdg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pdg RCSB]</span>
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'''CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB'''
'''CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB'''
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[[Category: Oefner, C.]]
[[Category: Oefner, C.]]
[[Category: Winkler, F K.]]
[[Category: Winkler, F K.]]
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[[Category: growth factor]]
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[[Category: Growth factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:57:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:58:15 2008''
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Revision as of 01:57, 3 May 2008

Template:STRUCTURE 1pdg

CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB


Overview

The crystal structure of the homodimeric BB isoform of human recombinant platelet-derived growth factor (PDGF-BB) has been determined by X-ray analysis to 3.0 A resolution. The polypeptide chain is folded into two highly twisted antiparallel pairs of beta-strands and contains an unusual knotted arrangement of three intramolecular disulfide bonds. Dimerization leads to the clustering of three surface loops at each end of the elongated dimer, which most probably form the receptor recognition sites.

About this Structure

1PDG is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human platelet-derived growth factor BB., Oefner C, D'Arcy A, Winkler FK, Eggimann B, Hosang M, EMBO J. 1992 Nov;11(11):3921-6. PMID:1396586 Page seeded by OCA on Sat May 3 04:57:46 2008

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