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5k05

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==Crystal Structure of COMT in complex with 4-methyl-2-(4-methylphenyl)-5-(1H-pyrazol-5-yl)-1,3-thiazole==
==Crystal Structure of COMT in complex with 4-methyl-2-(4-methylphenyl)-5-(1H-pyrazol-5-yl)-1,3-thiazole==
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<StructureSection load='5k05' size='340' side='right' caption='[[5k05]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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<StructureSection load='5k05' size='340' side='right'caption='[[5k05]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k05]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K05 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K05 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6P5:4-METHYL-2-(4-METHYLPHENYL)-5-(1H-PYRAZOL-5-YL)-1,3-THIAZOLE'>6P5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6P5:4-METHYL-2-(4-METHYLPHENYL)-5-(1H-PYRAZOL-5-YL)-1,3-THIAZOLE'>6P5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Comt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_O-methyltransferase Catechol O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.6 2.1.1.6] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_O-methyltransferase Catechol O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.6 2.1.1.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k05 OCA], [http://pdbe.org/5k05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k05 RCSB], [http://www.ebi.ac.uk/pdbsum/5k05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k05 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k05 OCA], [http://pdbe.org/5k05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k05 RCSB], [http://www.ebi.ac.uk/pdbsum/5k05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k05 ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 5k05" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5k05" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Catechol O-methyltransferase 3D structures|Catechol O-methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
[[Category: Catechol O-methyltransferase]]
[[Category: Catechol O-methyltransferase]]
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[[Category: Large Structures]]
[[Category: Ehler, A]]
[[Category: Ehler, A]]
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[[Category: RODRIGUEZ-SARMIENTO, R M]]
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[[Category: Rodriguez-Sarmiento, R M]]
[[Category: Rudolph, M G]]
[[Category: Rudolph, M G]]
[[Category: Catechol]]
[[Category: Catechol]]

Revision as of 05:59, 12 June 2019

Crystal Structure of COMT in complex with 4-methyl-2-(4-methylphenyl)-5-(1H-pyrazol-5-yl)-1,3-thiazole

PDB ID 5k05

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