5ejh

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'''Unreleased structure'''
 
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The entry 5ejh is ON HOLD until Paper Publication
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==Crystal structure of NAD kinase V98S mutant from Listeria monocytogenes==
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<StructureSection load='5ejh' size='340' side='right' caption='[[5ejh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Poncet-Montange, G., Assairi, L., Gelin, M., Pochet, S., Labesse, G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ejh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EJH FirstGlance]. <br>
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Description: Crystal structure of NAD kinase V98S mutant from Listeria monocytogenes
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ejh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ejh OCA], [http://pdbe.org/5ejh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ejh RCSB], [http://www.ebi.ac.uk/pdbsum/5ejh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ejh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NADK1_LISMO NADK1_LISMO]] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[HAMAP-Rule:MF_00361]<ref>PMID:17686780</ref> <ref>PMID:22608967</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Assairi, L]]
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[[Category: Gelin, M]]
[[Category: Labesse, G]]
[[Category: Labesse, G]]
[[Category: Pochet, S]]
[[Category: Pochet, S]]
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[[Category: Gelin, M]]
 
[[Category: Poncet-Montange, G]]
[[Category: Poncet-Montange, G]]
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[[Category: Assairi, L]]
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[[Category: Allostery]]
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[[Category: Citrate]]
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[[Category: Gram-positive nad kinase]]
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[[Category: Transferase]]

Revision as of 19:45, 9 December 2016

Crystal structure of NAD kinase V98S mutant from Listeria monocytogenes

5ejh, resolution 2.00Å

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