This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5t48
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact== | |
| - | + | <StructureSection load='5t48' size='340' side='right' caption='[[5t48]], [[Resolution|resolution]] 2.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5t48]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T48 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T48 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MGP:7-METHYL-GUANOSINE-5-TRIPHOSPHATE'>MGP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t48 OCA], [http://pdbe.org/5t48 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t48 RCSB], [http://www.ebi.ac.uk/pdbsum/5t48 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t48 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IF4E_DROME IF4E_DROME]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.<ref>PMID:8663200</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chung, M Y]] | ||
| + | [[Category: Gruener, S]] | ||
| + | [[Category: Igreja, C]] | ||
| + | [[Category: Izaurralde, E]] | ||
| + | [[Category: Peter, D]] | ||
| + | [[Category: Valkov, E]] | ||
| + | [[Category: Weber, R]] | ||
| + | [[Category: Weichenrieder, O]] | ||
| + | [[Category: Wohlbold, L]] | ||
| + | [[Category: 4e-binding protein]] | ||
| + | [[Category: Cap binding protein]] | ||
| + | [[Category: Eif4f]] | ||
| + | [[Category: Gene regulation]] | ||
| + | [[Category: Translation]] | ||
| + | [[Category: Translation initiation]] | ||
Revision as of 18:50, 26 October 2016
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
| |||||||||||
