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5jfg
From Proteopedia
(Difference between revisions)
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==Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA== | ==Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA== | ||
| - | <StructureSection load='5jfg' size='340' side='right' caption='[[5jfg]], [[Resolution|resolution]] 1.77Å' scene=''> | + | <StructureSection load='5jfg' size='340' side='right'caption='[[5jfg]], [[Resolution|resolution]] 1.77Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5jfg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JFG OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5jfg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JFG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JFG FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">radA, PF1926 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jfg OCA], [http://pdbe.org/5jfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jfg RCSB], [http://www.ebi.ac.uk/pdbsum/5jfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jfg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | [[http://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Resolvase 3D structures|Resolvase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Atcc 43587]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Abell, C]] | [[Category: Abell, C]] | ||
[[Category: Blundell, T L]] | [[Category: Blundell, T L]] | ||
Revision as of 07:46, 10 June 2020
Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA
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Categories: Atcc 43587 | Large Structures | Abell, C | Blundell, T L | Fischer, G | Hyvonen, M | Marsh, M | Morgan, M | Moschetti, T | Ng, H | Scott, D | Sharpe, T | Skidmore, J | Venkitaraman, A | Dna repair | Fragment based drug design | Humanisation | Hydrolase
