5gn8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a 48-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign== | |
| - | + | <StructureSection load='5gn8' size='340' side='right' caption='[[5gn8]], [[Resolution|resolution]] 2.81Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5gn8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GN8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gn8 OCA], [http://pdbe.org/5gn8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gn8 RCSB], [http://www.ebi.ac.uk/pdbsum/5gn8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gn8 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ferroxidase]] | ||
[[Category: Mikami, B]] | [[Category: Mikami, B]] | ||
[[Category: Zang, J]] | [[Category: Zang, J]] | ||
| + | [[Category: Zhang, S]] | ||
[[Category: Zhao, G]] | [[Category: Zhao, G]] | ||
| + | [[Category: Ferritin]] | ||
| + | [[Category: Nanocage]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Subunit interface redesign]] | ||
Revision as of 19:15, 15 December 2016
Structure of a 48-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign
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