5h8x
From Proteopedia
(Difference between revisions)
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==Crystal structure of the complex MMP-8/BF471 (catechol inhibitor)== | ==Crystal structure of the complex MMP-8/BF471 (catechol inhibitor)== | ||
| - | <StructureSection load='5h8x' size='340' side='right' caption='[[5h8x]], [[Resolution|resolution]] 1.30Å' scene=''> | + | <StructureSection load='5h8x' size='340' side='right'caption='[[5h8x]], [[Resolution|resolution]] 1.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5h8x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H8X OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5h8x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H8X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5H8X FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5XT:~{N}-[3,4-BIS(OXIDANYL)PHENYL]-4-PHENYL-BENZENESULFONAMIDE'>5XT</scene>, <scene name='pdbligand=7FY:~{N}-[4,5-BIS(OXIDANYLIDENE)CYCLOHEXEN-1-YL]-4-PHENYL-BENZENESULFONAMIDE'>7FY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5XT:~{N}-[3,4-BIS(OXIDANYL)PHENYL]-4-PHENYL-BENZENESULFONAMIDE'>5XT</scene>, <scene name='pdbligand=7FY:~{N}-[4,5-BIS(OXIDANYLIDENE)CYCLOHEXEN-1-YL]-4-PHENYL-BENZENESULFONAMIDE'>7FY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMP8, CLG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5h8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h8x OCA], [http://pdbe.org/5h8x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h8x RCSB], [http://www.ebi.ac.uk/pdbsum/5h8x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h8x ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5h8x" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5h8x" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Neutrophil collagenase]] | [[Category: Neutrophil collagenase]] | ||
[[Category: Capelli, D]] | [[Category: Capelli, D]] | ||
Revision as of 06:55, 20 May 2020
Crystal structure of the complex MMP-8/BF471 (catechol inhibitor)
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