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Androgen receptor

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C: DNA binding domain (DBD)<br />
C: DNA binding domain (DBD)<br />
D: Hinge region between DBD and LBD<br />
D: Hinge region between DBD and LBD<br />
-
E: Ligand binding domain (LBD) containing an <scene name='54/543362/Cv/2'>active site</scene> which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif.<ref>PMID:18805694</ref> <br />
+
E: Ligand binding domain (LBD) containing an <scene name='54/543362/Cv/3'>active site</scene> which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif.<ref>PMID:18805694</ref> <br />
F: C-terminal domain
F: C-terminal domain
</StructureSection>
</StructureSection>

Revision as of 13:34, 4 March 2018

Human androgen receptor ligand-binding domain complex with modulator (PDB code 3b5r)

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3D Structures of androgen receptor

Updated on 04-March-2018

See Also

References

  1. ↑ Bohl CE, Wu Z, Chen J, Mohler ML, Yang J, Hwang DJ, Mustafa S, Miller DD, Bell CE, Dalton JT. Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5567-70. Epub 2008 Sep 5. PMID:18805694 doi:10.1016/j.bmcl.2008.09.002
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