Sandbox 54321

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Function

Structure

is a synthetic angiotensin-converting enzyme inhibitor (ACE inhibitors) with molecular formula of C_21 H_31 N_3 O_5, empirical formula of C_21 H_31 N_3 O_5*H_2 O, and average molecular weight of 405.495 g/mol. It is primarily used for the treatment of hypertension. Lisinopril is typically in the trans isometric form because it has a lower steric repulsion between the hydroxyl and carboxyl groups than the cis conformation and is biologically active in this form (Bouabdallah).Lisinopril has a benzene ring and from there it has a 4-carbon amide chain where it branches of into a carboxylic acid group one way and a secondary amide group the other way which connects to the rest of the molecule. From the secondary amide, the molecule branches into a 5-carbon amine with a primary amide at the end. The other branch from the secondary amide has a ketone bonded to a nitrogen in a 4-carbon ring. From this carbon ring, there is a carboxylic acid group.

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Structural highlights

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