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Aldose Reductase
From Proteopedia
(Difference between revisions)
| Line 33: | Line 33: | ||
**[[2bgq]] – bAldR - barley<br /> | **[[2bgq]] – bAldR - barley<br /> | ||
**[[2bgs]] - bAldR+NADP<br /> | **[[2bgs]] - bAldR+NADP<br /> | ||
| - | **[[4gca]] – AldR – mouse<br /> | ||
| - | **[[4hbk]] – AldR – ''Schistosoma japonicum''<br /> | ||
*Aldose Reductase+inhibitors | *Aldose Reductase+inhibitors | ||
| Line 44: | Line 42: | ||
**[[1z89]], [[1z8a]] - hAldR+NADP+sulfonyl-pyridazinone<br /> | **[[1z89]], [[1z8a]] - hAldR+NADP+sulfonyl-pyridazinone<br /> | ||
**[[2pdg]], [[2pdh]] - hAldR+NADP+uracil inhibitor<br /> | **[[2pdg]], [[2pdh]] - hAldR+NADP+uracil inhibitor<br /> | ||
| - | ** | + | **[[1x96]], [[2acs]], [[2acu]] - hAldR+NADP+citrate<br /> |
**[[2acq]] - hAldR +NADP+glucose phosphate<br /> | **[[2acq]] - hAldR +NADP+glucose phosphate<br /> | ||
**[[2acr]] - hAldR +NADP+cacodylate<br /> | **[[2acr]] - hAldR +NADP+cacodylate<br /> | ||
| Line 61: | Line 59: | ||
**[[3lbo]], [[3ld5]], [[3lql]], [[3lz5]], [[2pdc]], [[3lep]], [[3lqg]], [[3lz3]], [[3m4h]], [[2pdj]], [[2pdp]], [[2pdu]], [[3m64]], [[3mc5]] - hAldR (mutant)+IDD inhibitors<br /> | **[[3lbo]], [[3ld5]], [[3lql]], [[3lz5]], [[2pdc]], [[3lep]], [[3lqg]], [[3lz3]], [[3m4h]], [[2pdj]], [[2pdp]], [[2pdu]], [[3m64]], [[3mc5]] - hAldR (mutant)+IDD inhibitors<br /> | ||
**[[3dn5]] – hAldR+NADP+biaryl inhibitor<br /> | **[[3dn5]] – hAldR+NADP+biaryl inhibitor<br /> | ||
| - | **[[4gq0]] - hAldR+NADP+ phenol derivative<br /> | ||
**[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br /> | **[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br /> | ||
**[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br /> | **[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br /> | ||
Revision as of 07:42, 28 December 2016
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3D Structures of Aldose Reductase
Updated on 28-December-2016
References
- ↑ Rondeau JM, Tete-Favier F, Podjarny A, Reymann JM, Barth P, Biellmann JF, Moras D. Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Nature. 1992 Jan 30;355(6359):469-72. PMID:1734286 doi:http://dx.doi.org/10.1038/355469a0
- ↑ Wilson DK, Bohren KM, Gabbay KH, Quiocho FA. An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science. 1992 Jul 3;257(5066):81-4. PMID:1621098
