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Carbidopa

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== Carbidopa ==
== Carbidopa ==
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<StructureSection load='1js3' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='1js3' size='340' side='right' caption='Crystal structure of DOPA Decarboxylase in complex with the inhibitor carbidopa' scene=''>
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<scene name='pdbligand=142:CARBIDOPA'>Carbidopa</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><scene name='74/746001/Active_site_dopa/4'>Active Site</scene>
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<scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><scene name='74/746001/Active_site_dopa/4'>Active Site</scene>
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This is a default text for your page '''Carbidopa'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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<scene name='pdbligand=142:CARBIDOPA'>Carbidopa</scene> inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC)<ref name="one">PMID:11106255</ref>
== Disease ==
== Disease ==

Revision as of 05:48, 15 November 2016

Carbidopa

Crystal structure of DOPA Decarboxylase in complex with the inhibitor carbidopa

Drag the structure with the mouse to rotate

References

  1. ↑ Gilbert JA, Frederick LM, Ames MM. The aromatic-L-amino acid decarboxylase inhibitor carbidopa is selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells. Clin Cancer Res. 2000 Nov;6(11):4365-72. PMID:11106255

Proteopedia Page Contributors and Editors (what is this?)

Victoria Markunas, Andrew Warzinski

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