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Lactate Dehydrogenase

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Line 66: Line 66:
**[[4lmr]], [[4ln1]] - LDH – ''Bacillus cereus''<br />
**[[4lmr]], [[4ln1]] - LDH – ''Bacillus cereus''<br />
**[[3vpg]] – TcLDH – ''Thermus caldophilus''<br />
**[[3vpg]] – TcLDH – ''Thermus caldophilus''<br />
 +
**[[3wsv]] – EmLDH – ''Enteroccocus mundtii''<br />
 +
**[[4l4r]], [[4ojn]] – hLDH A chain – human<br />
 +
**[[4uum]] – TvL-LDH – ''Trichomonas vaginalis''<br />
 +
**[[4uul]] – TvL-LDH (mutant)<br />
 +
**[[5hs4]] - PvL-LDH – ''Plasmodium vivax''<br />
 +
**[[5k0z]] – LDH B chain – chicken<br />
*L-LDH from yeast (cytochrome b2)
*L-LDH from yeast (cytochrome b2)
Line 84: Line 90:
**[[1ez4]] - L-LDH + NAD – ''Lactobacillus pentosus''<BR />
**[[1ez4]] - L-LDH + NAD – ''Lactobacillus pentosus''<BR />
**[[1lld]], [[2ldb]] - GsL-LDH + NAD<BR />
**[[1lld]], [[2ldb]] - GsL-LDH + NAD<BR />
-
**[[2a92]] – PvL-LDH + NAD – ''Plasmodium vivax'' <BR />
+
**[[2a92]] – PvL-LDH + NAD <BR />
**[[2a94]], [[2aa3]] - PvL-LDH + NAD-analog<br />
**[[2a94]], [[2aa3]] - PvL-LDH + NAD-analog<br />
 +
**[[5hru]], [[5hto]] - PvL-LDH + DNA<br />
**[[1u4o]], [[1u4s]], [[1u5a]], [[1xiv]] – PfL-LDH + inhibitor<BR />
**[[1u4o]], [[1u4s]], [[1u5a]], [[1xiv]] – PfL-LDH + inhibitor<BR />
**[[2xxb]] – TtL-LDH (mutant) + AMP<br />
**[[2xxb]] – TtL-LDH (mutant) + AMP<br />
Line 91: Line 98:
**[[3vkv]] - LcLDH + fructose-bisphosphate<br />
**[[3vkv]] - LcLDH + fructose-bisphosphate<br />
**[[3vpf]] – LcLDH (mutant) + pyruvate<br />
**[[3vpf]] – LcLDH (mutant) + pyruvate<br />
-
**[[4aj1]], [[4aj2]], [[4aj4]], [[4aje]], [[4ajh]], [[4aji]], [[4ajj]], [[4ajk]], [[4ajl]], [[4ajn]], [[4ajo]], [[4al4]] – LDH α chain + inhibitor – rat<br />
+
**[[4aj1]], [[4aj2]], [[4aj4]], [[4aje]], [[4ajh]], [[4aji]], [[4ajj]], [[4ajk]], [[4ajl]], [[4ajn]], [[4ajo]], [[4al4]], [[5kkc]] – raL-LDH A chain + inhibitor – rat<br />
-
**[[4ajp]], [[4m49]] – hLDH α chain + inhibitor - human<br />
+
**[[5es3]] – raL-LDH + oxamate<br />
 +
**[[5nqb]] – raL-LDH A chain (mutant) + malonate<br />
 +
**[[4ajp]], [[4m49]], [[4qsm]], [[4qt0]] – hLDH A chain + inhibitor <br />
 +
**[[4l4s]] – hLDH α chain + NAD <br />
**[[4i8x]], [[4i9h]], [[4i9n]], [[4i9u]] – rLDH A chain + pyridine derivative - rabbit<br />
**[[4i8x]], [[4i9h]], [[4i9n]], [[4i9u]] – rLDH A chain + pyridine derivative - rabbit<br />
 +
**[[4uun]] – TvL-LDH + NAD<br />
*''L-LDH ternary complex with inhibitor''
*''L-LDH ternary complex with inhibitor''
Line 100: Line 111:
**[[1t24]], [[1t25]], [[1t26]] - PfL-LDH + azole derivative + NAD<BR />
**[[1t24]], [[1t25]], [[1t26]] - PfL-LDH + azole derivative + NAD<BR />
**[[1t2e]] - PfL-LDH (mutant) + oxamate + NAD<BR />
**[[1t2e]] - PfL-LDH (mutant) + oxamate + NAD<BR />
-
**[[1ldg]] - PfL-LDH + oxamate + NAD<BR />
+
**[[1ldg]], [[4plz]] - PfL-LDH + oxamate + NAD<BR />
 +
**[[1t2d]] - PfL-LDH + oxalate + NAD<BR />
**[[2xxj]] – TtL-LDH (mutant) + oxamate + NAD<BR />
**[[2xxj]] – TtL-LDH (mutant) + oxamate + NAD<BR />
**[[2v7p]] - TtL-LDH + oxamate + NAD<BR />
**[[2v7p]] - TtL-LDH + oxamate + NAD<BR />
**[[3om9]], [[3czm]] – TgL-LDH + OXQ + NAD<BR />
**[[3om9]], [[3czm]] – TgL-LDH + OXQ + NAD<BR />
 +
**[[1sow]], [[1pzh]] - TgL-LDH + oxalate + NAD<BR />
 +
**[[1pzf]] - TgL-LDH + oxalate + NAD-analog<br />
 +
**[[1pzg]] - TgL-LDH + sulfate + NAD-analog<br />
**[[3h3f]] – rL-LDH A chain + oxamate + NAD <BR />
**[[3h3f]] – rL-LDH A chain + oxamate + NAD <BR />
 +
**[[5nqq]] - rL-LDH A chain + oxalacetate + NAD<br />
**[[4nd1]] - CpLDH + oxamate + NAD<BR />
**[[4nd1]] - CpLDH + oxamate + NAD<BR />
**[[1t2f]] - hL-LDH B chain + azole derivative + NAD <BR />
**[[1t2f]] - hL-LDH B chain + azole derivative + NAD <BR />
**[[1i0z]] - hL-LDH H chain + oxamate + NAD<BR />
**[[1i0z]] - hL-LDH H chain + oxamate + NAD<BR />
**[[1i10]] - hL-LDH M chain + oxamate + NAD<BR />
**[[1i10]] - hL-LDH M chain + oxamate + NAD<BR />
-
**[[4jnk]] - hL-LDH A chain + inhibitor + lactate + NAD<br />
+
**[[4qo7]], [[4qo8]], [[4r68]], [[4r69]], [[4rls]], [[4zvv]], [[5ixs]], [[5ixy]] - hL-LDH A chain + inhibitor + NAD<br />
-
**[[3vph]] - TcLDH + oxamate + NAD + fructose diphosphate<br />
+
**[[3wsw]] – EmL-LDH + NAD + fructose diphosphate<br />
**[[1oc4]] – L-LDH + oxamate + NAD – ''Plasmodium berghei''<BR />
**[[1oc4]] – L-LDH + oxamate + NAD – ''Plasmodium berghei''<BR />
**[[1a5z]] - L-LDH + oxamate + NAD – ''Thermotoga maritim''a<BR />
**[[1a5z]] - L-LDH + oxamate + NAD – ''Thermotoga maritim''a<BR />
**[[1lth]] - L-LDH + oxamate + NAD – ''Bifidobacterium longum''<BR />
**[[1lth]] - L-LDH + oxamate + NAD – ''Bifidobacterium longum''<BR />
**[[1ldn]] - GsL-LDH + oxamate + NAD<BR />
**[[1ldn]] - GsL-LDH + oxamate + NAD<BR />
-
**[[9ldb]], [[9ldt]] - pL-LDH + oxamate + NAD – pig
+
**[[9ldb]], [[9ldt]] - pL-LDH + oxamate + NAD – pig<br />
 +
**[[4plc]], [[4plf]] – ApLDH + NAD + pyruvate - ''Apicomplexa''<br />
 +
**[[4plg]] – ApLDH + NAD + oxamate <br />
 +
**[[5a1t]] – TvL-LDH + NAD + oxamate<br />
*''L-LDH ternary complex with reactants''
*''L-LDH ternary complex with reactants''
-
**[[1sow]], [[1pzh]] - TgL-LDH + oxalate + NAD<BR />
 
-
**[[1t2d]] - PfL-LDH + oxalate + NAD<BR />
 
-
**[[1pzf]] - TgL-LDH + oxalate + NAD-analog<br />
 
-
**[[1pzg]] - TgL-LDH + sulfate + NAD-analog<br />
 
**[[3h3j]] – SaL-LDH (mutant) + pyruvate + NAD<BR />
**[[3h3j]] – SaL-LDH (mutant) + pyruvate + NAD<BR />
**[[3d4p]] - SaL-LDH + pyruvate + NAD<BR />
**[[3d4p]] - SaL-LDH + pyruvate + NAD<BR />
Line 131: Line 146:
**[[3ldh]] - sdLDH + pyruvate + NAD<BR />
**[[3ldh]] - sdLDH + pyruvate + NAD<BR />
**[[3pqd]] - BsLDH + fructose-bisphosphate + NAD
**[[3pqd]] - BsLDH + fructose-bisphosphate + NAD
 +
 +
*L-LDH quaternary complex
 +
 +
**[[4jnk]] - hL-LDH A chain + inhibitor + lactate + NAD<br />
 +
**[[4okn]] - hL-LDH A chain + katamycin+ oxalate + NAD<br />
 +
**[[3vph]] - TcL-LDH + oxamate + NAD + fructose diphosphate<br />
*D-LDH
*D-LDH
Line 138: Line 159:
**[[1j4a]] - LdD-LDH + sulfate<BR />
**[[1j4a]] - LdD-LDH + sulfate<BR />
**[[1f0x]] – EcD-LDH + FAD – ''Escherichia coli''<BR />
**[[1f0x]] – EcD-LDH + FAD – ''Escherichia coli''<BR />
-
**[[2dld]] - D-LDH + oxamate + NAD – ''Lactobacillus helveticus''
+
**[[2dld]] - D-LDH + oxamate + NAD – ''Lactobacillus helveticus''<br />
 +
**[[3wwy]] – D-LDH – ''Fusobacterium nucleatum''<br />
 +
**[[3wwz]] – D-LDH – ''Peudomonas aeruginosa''<br />
 +
**[[4xkj]] – D-LDH + NAD – ''Sporolactobacillus inulinus''<br />
*L-LDH II
*L-LDH II

Revision as of 10:14, 29 June 2017

Lactate dehydrogenase dimer complex with cofactor NAD and pyruvate (PDB code 2fm3)

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3D structures of lactate dehydrogenase

Updated on 29-June-2017

Additional Information

For additional information, see Carbohydrate Metabolism

Reference

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