Protein kinase C
From Proteopedia
(Difference between revisions)
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*PKC-α | *PKC-α | ||
| - | **[[1dsy]], [[3rdj]], [[3twy]] – rCPKC-α C2 domain – rat | + | **[[1dsy]], [[3rdj]], [[3twy]], [[2nce]] – rCPKC-α C2 domain – rat |
**[[4l1l]] - rCPKC-α C2 domain + ion | **[[4l1l]] - rCPKC-α C2 domain + ion | ||
| Line 31: | Line 31: | ||
**[[2eli]] – hCPKC-α C1 domain – human – NMR<br /> | **[[2eli]] – hCPKC-α C1 domain – human – NMR<br /> | ||
**[[4dnl]] - hCPKC-α C2 domain<br /> | **[[4dnl]] - hCPKC-α C2 domain<br /> | ||
| - | **[[3iw4]] - hCPKC-α kinase domain + inhibitor | + | **[[3iw4]], [[4ra4]] - hCPKC-α kinase domain + inhibitor |
*PKC-β | *PKC-β | ||
| - | **[[1a25]] – rCPKC-β C2 domain | + | **[[1a25]] – rCPKC-β C2 domain<br /> |
| + | **[[3pfq]] - rCPKC-b II<br /> | ||
*PKC-β2 | *PKC-β2 | ||
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**[[1xjd]] – hNPKC-θ + saurosporine | **[[1xjd]] – hNPKC-θ + saurosporine | ||
| - | **[[2jed]] - hNPKC-θ kinase domain + inhibitor | + | **[[2jed]], [[4q9z]], [[5f9e]], [[4ra5]] - hNPKC-θ kinase domain + inhibitor |
*'''Atypical PKC''' | *'''Atypical PKC''' | ||
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**[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br /> | **[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br /> | ||
**[[4dc2]] - hAPKC-ι residues 231-595 + PAR3 peptide<br /> | **[[4dc2]] - hAPKC-ι residues 231-595 + PAR3 peptide<br /> | ||
| + | **[[5lih]] - hAPKC-ι kinase domain + PKC-εζ peptide<br /> | ||
*PKC-ν | *PKC-ν | ||
**[[2d9z]] – hPKC-ν PH domain - NMR | **[[2d9z]] – hPKC-ν PH domain - NMR | ||
| + | |||
| + | *PKC-ζ | ||
| + | |||
| + | **[[4mjs]] - rPKC-ζ + sequestosome-1<br /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 22:33, 20 September 2017
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3D structures of protein kinase C
Updated on 20-September-2017
References
- ↑ Idris I, Gray S, Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia. 2001 Jun;44(6):659-73. PMID:11440359 doi:http://dx.doi.org/10.1007/s001250051675
- ↑ Koya D, King GL. Protein kinase C activation and the development of diabetic complications. Diabetes. 1998 Jun;47(6):859-66. PMID:9604860
- ↑ Koivunen J, Aaltonen V, Peltonen J. Protein kinase C (PKC) family in cancer progression. Cancer Lett. 2006 Apr 8;235(1):1-10. PMID:15907369 doi:http://dx.doi.org/10.1016/j.canlet.2005.03.033
- ↑ Guerrero-Valero M, Ferrer-Orta C, Querol-Audi J, Marin-Vicente C, Fita I, Gomez-Fernandez JC, Verdaguer N, Corbalan-Garcia S. Structural and mechanistic insights into the association of PKC{alpha}-C2 domain to PtdIns(4,5)P2. Proc Natl Acad Sci U S A. 2009 Apr 3. PMID:19346474
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