1pzb

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[[Image:1pzb.jpg|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_1pzb", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>
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{{STRUCTURE_1pzb| PDB=1pzb | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzb OCA], [http://www.ebi.ac.uk/pdbsum/1pzb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pzb RCSB]</span>
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'''THE CRYSTAL STRUCTURES OF REDUCED PSEUDOAZURIN FROM ALCALIGENES FAECALIS S-6 AT TWO PH VALUES'''
'''THE CRYSTAL STRUCTURES OF REDUCED PSEUDOAZURIN FROM ALCALIGENES FAECALIS S-6 AT TWO PH VALUES'''
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Petratos, K.]]
[[Category: Petratos, K.]]
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[[Category: electron transfer(cuproprotein)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:40:27 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:06:37 2008''
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Revision as of 02:40, 3 May 2008

Image:1pzb.jpg

Template:STRUCTURE 1pzb

THE CRYSTAL STRUCTURES OF REDUCED PSEUDOAZURIN FROM ALCALIGENES FAECALIS S-6 AT TWO PH VALUES


Overview

The structures of the reduced (Cu1+) blue-copper protein pseudoazurin from Alcaligenes faecalis strain S-6 are refined at pH 7.8 and 4.4 using X-ray diffraction data to 1.8 A resolution. The final R-factors for the high and low pH structures are 0.178 and 0.177, respectively. Comparing the reduced pseudoazurin at pH 7.8 with the oxidised (Cu2+) molecule, small changes are observed in the vicinity of the copper site and on the protein surface. At pH 4.4 the copper substituent imidazole of His81 rotates away from the metal with a concurrent movement of the latter towards the plane of the remaining three ligands (S gamma-Cys78, N delta 1-His40 and S delta-Met86) thus the geometry of the copper site becomes planar trigonal.

About this Structure

1PZB is a Single protein structure of sequence from Alcaligenes faecalis. Full crystallographic information is available from OCA.

Reference

The crystal structures of reduced pseudoazurin from Alcaligenes faecalis S-6 at two pH values., Vakoufari E, Wilson KS, Petratos K, FEBS Lett. 1994 Jun 27;347(2-3):203-6. PMID:8034003 Page seeded by OCA on Sat May 3 05:40:27 2008

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