5mev
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 21== | |
| - | + | <StructureSection load='5mev' size='340' side='right' caption='[[5mev]], [[Resolution|resolution]] 2.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5mev]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MEV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7LW:(5~{R},13~{S},17~{S})-5-[(3,4-DICHLOROPHENYL)METHYL]-8-METHYL-13-[(4-METHYLSULFONYLPHENYL)METHYL]-1,4,8,12,16-PENTAZATRICYCLO[15.8.1.0^{20,25}]HEXACOSA-20,22,24-TRIENE-3,7,15,26-TETRONE'>7LW</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mes|5mes]], [[5ku9|5ku9]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mev OCA], [http://pdbe.org/5mev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mev RCSB], [http://www.ebi.ac.uk/pdbsum/5mev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mev ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCL1_MOUSE MCL1_MOUSE]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hargreaves, D]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Mcl1 fab macrocycle]] | ||
| + | [[Category: Mcl1-fab_55_c6hi]] | ||
Revision as of 00:47, 19 January 2017
MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 21
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