1qgt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1qgt.gif|left|200px]]
[[Image:1qgt.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1qgt |SIZE=350|CAPTION= <scene name='initialview01'>1qgt</scene>, resolution 3.3&Aring;
+
The line below this paragraph, containing "STRUCTURE_1qgt", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1qgt| PDB=1qgt | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qgt OCA], [http://www.ebi.ac.uk/pdbsum/1qgt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qgt RCSB]</span>
+
-
}}
+
'''HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)'''
'''HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)'''
Line 28: Line 25:
[[Category: Leslie, A G.W.]]
[[Category: Leslie, A G.W.]]
[[Category: Wynne, S A.]]
[[Category: Wynne, S A.]]
-
[[Category: icosahedral virus]]
+
[[Category: Icosahedral virus]]
-
[[Category: viral capsid protein]]
+
[[Category: Viral capsid protein]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:15:09 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:13:21 2008''
+

Revision as of 03:15, 3 May 2008

Image:1qgt.gif

Template:STRUCTURE 1qgt

HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)


Overview

Hepatitis B is a small enveloped DNA virus that poses a major hazard to human health. The crystal structure of the T = 4 capsid has been solved at 3.3 A resolution, revealing a largely helical protein fold that is unusual for icosahedral viruses. The monomer fold is stabilized by a hydrophobic core that is highly conserved among human viral variants. Association of two amphipathic alpha-helical hairpins results in formation of a dimer with a four-helix bundle as the major central feature. The capsid is assembled from dimers via interactions involving a highly conserved region near the C terminus of the truncated protein used for crystallization. The major immunodominant region lies at the tips of the alpha-helical hairpins that form spikes on the capsid surface.

About this Structure

1QGT is a Single protein structure of sequence from Hepatitis b virus. Full crystallographic information is available from OCA.

Reference

The crystal structure of the human hepatitis B virus capsid., Wynne SA, Crowther RA, Leslie AG, Mol Cell. 1999 Jun;3(6):771-80. PMID:10394365 Page seeded by OCA on Sat May 3 06:15:09 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qgt"
Personal tools