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3spk

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==Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant==
==Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant==
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<StructureSection load='3spk' size='340' side='right' caption='[[3spk]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
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<StructureSection load='3spk' size='340' side='right'caption='[[3spk]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3spk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SPK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3spk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPV:N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE'>TPV</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TPV:N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE'>TPV</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tw7|1tw7]], [[1rpi|1rpi]], [[3oq7|3oq7]], [[3oqa|3oqa]], [[3oqd|3oqd]], [[3so9|3so9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tw7|1tw7]], [[1rpi|1rpi]], [[3oq7|3oq7]], [[3oqa|3oqa]], [[3oqd|3oqd]], [[3so9|3so9]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3spk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spk OCA], [http://pdbe.org/3spk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3spk RCSB], [http://www.ebi.ac.uk/pdbsum/3spk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3spk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spk OCA], [https://pdbe.org/3spk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spk RCSB], [https://www.ebi.ac.uk/pdbsum/3spk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spk ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Virus protease|Virus protease]]
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
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[[Category: Large Structures]]
[[Category: Brunzelle, J S]]
[[Category: Brunzelle, J S]]
[[Category: Kovari, I A]]
[[Category: Kovari, I A]]

Revision as of 08:05, 29 June 2022

Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant

PDB ID 3spk

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