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3q7f

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==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1==
==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1==
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<StructureSection load='3q7f' size='340' side='right' caption='[[3q7f]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3q7f' size='340' side='right'caption='[[3q7f]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3q7f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crynh Crynh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q7F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3q7f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crynh Crynh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3CX:(2S)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3CX</scene>, <scene name='pdbligand=ED2:N-BENZYL-N-(2-{(4-CYANOPHENYL)[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]AMINO}ETHYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE'>ED2</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CX:(2S)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3CX</scene>, <scene name='pdbligand=ED2:N-BENZYL-N-(2-{(4-CYANOPHENYL)[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]AMINO}ETHYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE'>ED2</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q73|3q73]], [[3q75|3q75]], [[3q78|3q78]], [[3q79|3q79]], [[3q7a|3q7a]], [[3sfx|3sfx]], [[3sfy|3sfy]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q73|3q73]], [[3q75|3q75]], [[3q78|3q78]], [[3q79|3q79]], [[3q7a|3q7a]], [[3sfx|3sfx]], [[3sfy|3sfy]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7f OCA], [http://pdbe.org/3q7f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q7f RCSB], [http://www.ebi.ac.uk/pdbsum/3q7f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7f OCA], [https://pdbe.org/3q7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7f RCSB], [https://www.ebi.ac.uk/pdbsum/3q7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7f ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Farnesyltransferase|Farnesyltransferase]]
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*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Crynh]]
[[Category: Crynh]]
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[[Category: Large Structures]]
[[Category: Beese, L S]]
[[Category: Beese, L S]]
[[Category: Hast, M A]]
[[Category: Hast, M A]]
[[Category: Protein prenyltransferase]]
[[Category: Protein prenyltransferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:56, 8 June 2022

Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1

PDB ID 3q7f

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