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3q7a
From Proteopedia
(Difference between revisions)
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==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123== | ==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123== | ||
| - | <StructureSection load='3q7a' size='340' side='right' caption='[[3q7a]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3q7a' size='340' side='right'caption='[[3q7a]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q7a]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crynh Crynh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7A FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=778:4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE'>778</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=778:4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE'>778</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q73|3q73]], [[3q75|3q75]], [[3q78|3q78]], [[3q79|3q79]], [[3q7f|3q7f]], [[3sfx|3sfx]], [[3sfy|3sfy]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q73|3q73]], [[3q75|3q75]], [[3q78|3q78]], [[3q79|3q79]], [[3q7f|3q7f]], [[3sfx|3sfx]], [[3sfy|3sfy]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7a OCA], [https://pdbe.org/3q7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7a RCSB], [https://www.ebi.ac.uk/pdbsum/3q7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7a ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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==See Also== | ==See Also== | ||
| - | *[[Farnesyltransferase|Farnesyltransferase]] | + | *[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Crynh]] | [[Category: Crynh]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Beese, L S]] | [[Category: Beese, L S]] | ||
[[Category: Hast, M A]] | [[Category: Hast, M A]] | ||
[[Category: Protein prenyltransferase]] | [[Category: Protein prenyltransferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 05:56, 8 June 2022
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123
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