5ja7

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==Human cathepsin K mutant C25S in complex with the allosteric effector NSC94914==
==Human cathepsin K mutant C25S in complex with the allosteric effector NSC94914==
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<StructureSection load='5ja7' size='340' side='right' caption='[[5ja7]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
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<StructureSection load='5ja7' size='340' side='right'caption='[[5ja7]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ja7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JA7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JA7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ja7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JA7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JA7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6HM:[([1,1-BIPHENYL]-2-YL)METHYL]PROPANEDIOIC+ACID'>6HM</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6HM:[([1,1-BIPHENYL]-2-YL)METHYL]PROPANEDIOIC+ACID'>6HM</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSK, CTSO, CTSO2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ja7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ja7 OCA], [http://pdbe.org/5ja7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ja7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ja7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ja7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ja7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ja7 OCA], [http://pdbe.org/5ja7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ja7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ja7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ja7 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5ja7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ja7" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cathepsin 3D structures|Cathepsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Cathepsin K]]
[[Category: Cathepsin K]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Korenc, M]]
[[Category: Korenc, M]]
[[Category: Lenarcic, B]]
[[Category: Lenarcic, B]]

Revision as of 07:39, 10 June 2020

Human cathepsin K mutant C25S in complex with the allosteric effector NSC94914

PDB ID 5ja7

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