This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4djp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal Structure of wild-type HIV-1 Protease in Complex with MKP73==
==Crystal Structure of wild-type HIV-1 Protease in Complex with MKP73==
-
<StructureSection load='4djp' size='340' side='right' caption='[[4djp]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
+
<StructureSection load='4djp' size='340' side='right'caption='[[4djp]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4djp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DJP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4djp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DJP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M73:METHYL+(2S)-3-({[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL][(2S)-2-METHYLBUTYL]AMINO}-1-PHENYLBUTAN-2-YL]CARBAMOYL}OXY)-2-METHYLPROPANOATE'>M73</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M73:METHYL+(2S)-3-({[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL][(2S)-2-METHYLBUTYL]AMINO}-1-PHENYLBUTAN-2-YL]CARBAMOYL}OXY)-2-METHYLPROPANOATE'>M73</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4djo|4djo]], [[4djq|4djq]], [[4djr|4djr]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4djp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4djp OCA], [https://pdbe.org/4djp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4djp RCSB], [https://www.ebi.ac.uk/pdbsum/4djp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4djp ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4djp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4djp OCA], [http://pdbe.org/4djp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4djp RCSB], [http://www.ebi.ac.uk/pdbsum/4djp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4djp ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/Q90K99_9HIV1 Q90K99_9HIV1]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 18:
</div>
</div>
<div class="pdbe-citations 4djp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4djp" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Nalam, M N.L]]
+
[[Category: Human immunodeficiency virus 1]]
-
[[Category: Schiffer, C A]]
+
[[Category: Large Structures]]
-
[[Category: Aid]]
+
[[Category: Nalam MNL]]
-
[[Category: Aspartyl protease]]
+
[[Category: Schiffer CA]]
-
[[Category: Drug design]]
+
-
[[Category: Drug resistance]]
+
-
[[Category: Hiv-1 protease]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Protease inhibitor]]
+

Revision as of 08:21, 21 September 2022

Crystal Structure of wild-type HIV-1 Protease in Complex with MKP73

PDB ID 4djp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools