This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qrq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1qrq.gif|left|200px]]
[[Image:1qrq.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1qrq |SIZE=350|CAPTION= <scene name='initialview01'>1qrq</scene>, resolution 2.80&Aring;
+
The line below this paragraph, containing "STRUCTURE_1qrq", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1qrq| PDB=1qrq | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qrq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qrq OCA], [http://www.ebi.ac.uk/pdbsum/1qrq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qrq RCSB]</span>
+
-
}}
+
'''STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT'''
'''STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT'''
Line 28: Line 25:
[[Category: MacKinnon, R.]]
[[Category: MacKinnon, R.]]
[[Category: Mann, S.]]
[[Category: Mann, S.]]
-
[[Category: aldo-keto reductase]]
+
[[Category: Aldo-keto reductase]]
-
[[Category: metal transport]]
+
[[Category: Metal transport]]
-
[[Category: potassium channel subunit]]
+
[[Category: Potassium channel subunit]]
-
[[Category: tim barrel]]
+
[[Category: Tim barrel]]
-
[[Category: voltage-dependent potassium channel]]
+
[[Category: Voltage-dependent potassium channel]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:37:44 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:18:05 2008''
+

Revision as of 03:37, 3 May 2008

Image:1qrq.gif

Template:STRUCTURE 1qrq

STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT


Overview

The integral membrane subunits of many voltage-dependent potassium channels are associated with an additional protein known as the beta subunit. One function of beta subunits is to modify K+ channel gating. We have determined the structure of the conserved core of mammalian beta subunits by X-ray crystallography at 2.8 A resolution. Like the integral membrane component of K+ channels, beta subunits form a four-fold symmetric structure. Each subunit is an oxidoreductase enzyme complete with a nicotinamide co-factor in its active site. Several structural features of the enzyme active site, including its location with respect to the four-fold axis, imply that it may interact directly or indirectly with the K+ channel's voltage sensor. This structure suggests a mechanism for coupling membrane electrical excitability directly to chemistry of the cell.

About this Structure

1QRQ is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Structure of a voltage-dependent K+ channel beta subunit., Gulbis JM, Mann S, MacKinnon R, Cell. 1999 Jun 25;97(7):943-52. PMID:10399921 Page seeded by OCA on Sat May 3 06:37:44 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qrq"
Personal tools