5bx1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of PRL-1 complex with compound analogy 3== | |
| - | + | <StructureSection load='5bx1' size='340' side='right' caption='[[5bx1]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5bx1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BX1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4XA:3-(5,6-DIMETHYL-2H-ISOINDOL-2-YL)-N-[(E)-FURAN-2-YLMETHYLIDENE]BENZOHYDRAZIDE'>4XA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zck|1zck]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bx1 OCA], [http://pdbe.org/5bx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5bx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bx1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TP4A1_HUMAN TP4A1_HUMAN]] Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.<ref>PMID:12235145</ref> <ref>PMID:14643450</ref> <ref>PMID:12782572</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Bai, Y]] | [[Category: Bai, Y]] | ||
| + | [[Category: Liu, S]] | ||
[[Category: Zhang, Z]] | [[Category: Zhang, Z]] | ||
| - | [[Category: | + | [[Category: Detrimerizer]] |
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Interface]] | ||
| + | [[Category: Monomer]] | ||
| + | [[Category: Protein tyrosine phosphatase]] | ||
Revision as of 21:36, 22 December 2016
Crystal Structure of PRL-1 complex with compound analogy 3
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