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5mlg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of rat prorenin== | |
| - | + | <StructureSection load='5mlg' size='340' side='right' caption='[[5mlg]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5mlg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MLG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MLG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mlg OCA], [http://pdbe.org/5mlg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mlg RCSB], [http://www.ebi.ac.uk/pdbsum/5mlg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mlg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RENI_RAT RENI_RAT]] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Renin]] | ||
[[Category: Read, R]] | [[Category: Read, R]] | ||
[[Category: Yan, Y]] | [[Category: Yan, Y]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Prorenin]] | ||
| + | [[Category: Rat]] | ||
Revision as of 06:10, 20 December 2017
Crystal structure of rat prorenin
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