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4fpy

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==Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate==
==Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate==
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<StructureSection load='4fpy' size='340' side='right' caption='[[4fpy]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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<StructureSection load='4fpy' size='340' side='right'caption='[[4fpy]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fpy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FPY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fpy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FPY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0V8:2-[(3-BROMOBENZYL)AMINO]ETHANESULFONIC+ACID'>0V8</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0V8:2-[(3-BROMOBENZYL)AMINO]ETHANESULFONIC+ACID'>0V8</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vw0|2vw0]], [[2vw1|2vw1]], [[2vw2|2vw2]], [[4foq|4foq]], [[4fov|4fov]], [[4fow|4fow]], [[4foy|4foy]], [[4fp2|4fp2]], [[4fp3|4fp3]], [[4fpc|4fpc]], [[4fpe|4fpe]], [[4fpf|4fpf]], [[4fpg|4fpg]], [[4fph|4fph]], [[4fpj|4fpj]], [[4fpk|4fpk]], [[4fpl|4fpl]], [[4fpo|4fpo]], [[4fq4|4fq4]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fpy OCA], [https://pdbe.org/4fpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fpy RCSB], [https://www.ebi.ac.uk/pdbsum/4fpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fpy ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nanB, SP_1687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 "Diplococcus pneumoniae" (Klein 1884) Weichselbaum 1886])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fpy OCA], [http://pdbe.org/4fpy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fpy RCSB], [http://www.ebi.ac.uk/pdbsum/4fpy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fpy ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NANB_STRPN NANB_STRPN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Exo-alpha-sialidase]]
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[[Category: Large Structures]]
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[[Category: Brear, P]]
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[[Category: Streptococcus pneumoniae]]
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[[Category: Drug design]]
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[[Category: Brear P]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-inhibitor complex]]
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[[Category: Intramolecular trans-sialidase]]
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[[Category: Neuraminidase]]
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Revision as of 20:04, 19 October 2022

Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate

PDB ID 4fpy

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