Poliovirus receptor-related protein

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<StructureSection load='4myw' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='4myw' size='340' side='right' caption='Poliovirus receptor-related protein 1 (green) complex with herpes virus envelope glycoprotein (grey) (PDB code [[4myw]])' scene=''>
== Function ==
== Function ==
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'''Poliovirus receptor-related protein''' (PVRP) or '''Nectin''' are membrane glycoproteins belonging to the immunoglobulin family<ref>PMID:21638687</ref>.<br />
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'''Poliovirus receptor-related protein''' (PVRP) or '''Nectin''' are membrane glycoproteins belonging to the immunoglobulin family.<br />
*'''PVRP-1''' mediates Ca+2-independent cell adhesion<ref>PMID:09616127</ref>.<br />
*'''PVRP-1''' mediates Ca+2-independent cell adhesion<ref>PMID:09616127</ref>.<br />
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*'''PVRP-2''' and '''PVRP-3''' are components of the adherens junction.<br />
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*'''PVRP-2''' and '''PVRP-3''' are components of the adherens junction<ref>PMID:9845526</ref>.<br />
*'''PVRP-4''' binds PVRP-1.<br />
*'''PVRP-4''' binds PVRP-1.<br />
== Relevance ==
== Relevance ==
PVRP-4 is involved in tumor cell migration.
PVRP-4 is involved in tumor cell migration.
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== Structural highlights ==
 
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</StructureSection>
</StructureSection>

Revision as of 10:44, 18 December 2016

Poliovirus receptor-related protein 1 (green) complex with herpes virus envelope glycoprotein (grey) (PDB code 4myw)

Drag the structure with the mouse to rotate

3D structures of poliovirus receptor-related protein

Updated on 18-December-2016

References

  1. Geraghty RJ, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG. Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor. Science. 1998 Jun 5;280(5369):1618-20. PMID:9616127
  2. Lopez M, Aoubala M, Jordier F, Isnardon D, Gomez S, Dubreuil P. The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule. Blood. 1998 Dec 15;92(12):4602-11. PMID:9845526

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman

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