DTDP-glucose 4,6-dehydratase
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
The RmlB structure is divided into 2 domains. The N-terminal NAD-binding domain which contains the Rossmann fold and the C-terminal sugar nucleotide binding domain<ref>PMID:11796113</ref>. | The RmlB structure is divided into 2 domains. The N-terminal NAD-binding domain which contains the Rossmann fold and the C-terminal sugar nucleotide binding domain<ref>PMID:11796113</ref>. | ||
+ | *<scene name='74/748855/Cv/2'>NAD binding site</scene>. | ||
+ | *<scene name='74/748855/Cv/3'>TDB-glucose binding site</scene>. | ||
+ | *<scene name='74/748855/Cv/4'>Whole active site</scene>. | ||
</StructureSection> | </StructureSection> |
Revision as of 09:29, 19 December 2016
|
3D structures of RmlB
Updated on 19-December-2016
1kep, 1oc2 – SsRmlB + NAD + TDP-xylose – Streptococcus suis
1ker – SsRmlB + NAD + TDP-glucose
1ket – SsRmlB + NAD + TDP
1keu – StRmlB + NAD + TDP-glucose – Salmonella typhimurium
1kew – StRmlB + NAD + TDP
1g1a – StRmlB + NAD
</StructureSection>
References
- ↑ Allard ST, Giraud MF, Whitfield C, Messner P, Naismith JH. The purification, crystallization and structural elucidation of dTDP-D-glucose 4,6-dehydratase (RmlB), the second enzyme of the dTDP-L-rhamnose synthesis pathway from Salmonella enterica serovar typhimurium. Acta Crystallogr D Biol Crystallogr. 2000 Feb;56(Pt 2):222-5. PMID:10666612
- ↑ Allard ST, Beis K, Giraud MF, Hegeman AD, Gross JW, Wilmouth RC, Whitfield C, Graninger M, Messner P, Allen AG, Maskell DJ, Naismith JH. Toward a structural understanding of the dehydratase mechanism. Structure. 2002 Jan;10(1):81-92. PMID:11796113