Survivin
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='3uig' size='340' side='right' caption='Structure of human survivin dimer ( | + | <StructureSection load='3uig' size='340' side='right' caption='Structure of human survivin dimer (magenta and green) complex with histone H3 peptide (cyan) and Zn+2 ion (grey) (PDB code [[3uig]]).' scene='59/596423/Cv/1'> |
== Function == | == Function == | ||
Revision as of 10:03, 14 June 2017
| |||||||||||
3D structures of survivin
Updated on 14-June-2017
References
- ↑ Tamm I, Wang Y, Sausville E, Scudiero DA, Vigna N, Oltersdorf T, Reed JC. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 1998 Dec 1;58(23):5315-20. PMID:9850056
- ↑ Carmena M, Wheelock M, Funabiki H, Earnshaw WC. The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol. 2012 Dec;13(12):789-803. doi: 10.1038/nrm3474. PMID:23175282 doi:http://dx.doi.org/10.1038/nrm3474
- ↑ Zaffaroni N, Costa A, Pennati M, De Marco C, Affini E, Madeo M, Erdas R, Cabras A, Kusamura S, Baratti D, Deraco M, Daidone MG. Survivin is highly expressed and promotes cell survival in malignant peritoneal mesothelioma. Cell Oncol. 2007;29(6):453-66. PMID:18032822
- ↑ Rodel F, Sprenger T, Kaina B, Liersch T, Rodel C, Fulda S, Hehlgans S. Survivin as a prognostic/predictive marker and molecular target in cancer therapy. Curr Med Chem. 2012;19(22):3679-88. PMID:22680927
