This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qzm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1qzm.gif|left|200px]]
[[Image:1qzm.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1qzm |SIZE=350|CAPTION= <scene name='initialview01'>1qzm</scene>, resolution 1.90&Aring;
+
The line below this paragraph, containing "STRUCTURE_1qzm", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_La Endopeptidase La], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.53 3.4.21.53] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE= LON ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1qzm| PDB=1qzm | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzm OCA], [http://www.ebi.ac.uk/pdbsum/1qzm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qzm RCSB]</span>
+
-
}}
+
'''alpha-domain of ATPase'''
'''alpha-domain of ATPase'''
Line 36: Line 33:
[[Category: Tropea, J E.]]
[[Category: Tropea, J E.]]
[[Category: Wlodawer, A.]]
[[Category: Wlodawer, A.]]
-
[[Category: aaa+ protein]]
+
[[Category: Aaa+ protein]]
-
[[Category: atp-dependent protease]]
+
[[Category: Atp-dependent protease]]
-
[[Category: hydrolase]]
+
[[Category: Hydrolase]]
-
[[Category: oligomerization domain]]
+
[[Category: Oligomerization domain]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:53:45 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:21:16 2008''
+

Revision as of 03:53, 3 May 2008

Template:STRUCTURE 1qzm

alpha-domain of ATPase


Overview

The crystal structure of the small, mostly helical alpha domain of the AAA+ module of the Escherichia coli ATP-dependent protease Lon has been solved by single isomorphous replacement combined with anomalous scattering and refined at 1.9A resolution to a crystallographic R factor of 17.9%. This domain, comprising residues 491-584, was obtained by chymotrypsin digestion of the recombinant full-length protease. The alpha domain of Lon contains four alpha helices and two parallel strands and resembles similar domains found in a variety of ATPases and helicases, including the oligomeric proteases HslVU and ClpAP. The highly conserved "sensor-2" Arg residue is located at the beginning of the third helix. Detailed comparison with the structures of 11 similar domains established the putative location of the nucleotide-binding site in this first fragment of Lon for which a crystal structure has become available.

About this Structure

1QZM is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution., Botos I, Melnikov EE, Cherry S, Khalatova AG, Rasulova FS, Tropea JE, Maurizi MR, Rotanova TV, Gustchina A, Wlodawer A, J Struct Biol. 2004 Apr-May;146(1-2):113-22. PMID:15037242 Page seeded by OCA on Sat May 3 06:53:45 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools