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5kcf

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==Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-ethyl, 4-methoxybenzyl OBHS-N derivative==
==Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-ethyl, 4-methoxybenzyl OBHS-N derivative==
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<StructureSection load='5kcf' size='340' side='right' caption='[[5kcf]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
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<StructureSection load='5kcf' size='340' side='right'caption='[[5kcf]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5kcf]] is a 4 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4zwk 4zwk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KCF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5kcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4zwk 4zwk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KCF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OB4:(1S,2R,4S)-N-ETHYL-5,6-BIS(4-HYDROXYPHENYL)-N-(4-METHOXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONAMIDE'>OB4</scene>, <scene name='pdbligand=OB5:(1R,2S,4R)-N-ETHYL-5,6-BIS(4-HYDROXYPHENYL)-N-(4-METHOXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONAMIDE'>OB5</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OB4:(1S,2R,4S)-N-ETHYL-5,6-BIS(4-HYDROXYPHENYL)-N-(4-METHOXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONAMIDE'>OB4</scene>, <scene name='pdbligand=OB5:(1R,2S,4R)-N-ETHYL-5,6-BIS(4-HYDROXYPHENYL)-N-(4-METHOXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONAMIDE'>OB5</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kcc|5kcc]], [[5kcd|5kcd]], [[5kct|5kct]], [[5kcu|5kcu]], [[5kcw|5kcw]], [[5kd9|5kd9]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kcc|5kcc]], [[5kcd|5kcd]], [[5kct|5kct]], [[5kcu|5kcu]], [[5kcw|5kcw]], [[5kd9|5kd9]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kcf OCA], [http://pdbe.org/5kcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kcf RCSB], [http://www.ebi.ac.uk/pdbsum/5kcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kcf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kcf OCA], [http://pdbe.org/5kcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kcf RCSB], [http://www.ebi.ac.uk/pdbsum/5kcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kcf ProSAT]</span></td></tr>
</table>
</table>
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</div>
</div>
<div class="pdbe-citations 5kcf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5kcf" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Estrogen receptor 3D structures|Estrogen receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Boonmuen, N]]
[[Category: Boonmuen, N]]
[[Category: Bruno, N E]]
[[Category: Bruno, N E]]

Revision as of 10:13, 26 February 2020

Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-ethyl, 4-methoxybenzyl OBHS-N derivative

PDB ID 5kcf

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