1r3m

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[[Image:1r3m.gif|left|200px]]
[[Image:1r3m.gif|left|200px]]
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{{Structure
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|PDB= 1r3m |SIZE=350|CAPTION= <scene name='initialview01'>1r3m</scene>, resolution 2.2&Aring;
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The line below this paragraph, containing "STRUCTURE_1r3m", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span>
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|GENE=
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{{STRUCTURE_1r3m| PDB=1r3m | SCENE= }}
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|RELATEDENTRY=[[1bsr|1BSR]], [[1r5c|1R5C]], [[1r5d|1R5D]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r3m OCA], [http://www.ebi.ac.uk/pdbsum/1r3m PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1r3m RCSB]</span>
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'''Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease'''
'''Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease'''
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[[Category: Sica, F.]]
[[Category: Sica, F.]]
[[Category: Zagari, A.]]
[[Category: Zagari, A.]]
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[[Category: hinge]]
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[[Category: Hinge]]
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[[Category: ribonuclease]]
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[[Category: Ribonuclease]]
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[[Category: swapping]]
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[[Category: Swapping]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:02:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:22:43 2008''
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Revision as of 04:02, 3 May 2008

Image:1r3m.gif

Template:STRUCTURE 1r3m

Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease


Overview

Bovine seminal ribonuclease is a unique case of protein dimorphism, since it exists in two dimeric forms, with different biological and kinetic behavior, which interconvert into one another through three-dimensional swapping. Here we report the crystal structure, at 2.2 A resolution, of the unswapped form of bovine seminal ribonuclease. Besides completing the structural definition of bovine seminal ribonuclease conformational dimorphism, this study provides the structural basis to explain the dependence of the enzyme cooperative effects on its swapping state.

About this Structure

1R3M is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease., Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L, FEBS Lett. 2003 Nov 6;554(1-2):105-10. PMID:14596923 Page seeded by OCA on Sat May 3 07:02:04 2008

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