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4nap

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Current revision (08:18, 11 January 2023) (edit) (undo)
 
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==Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan==
==Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan==
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<StructureSection load='4nap' size='340' side='right' caption='[[4nap]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='4nap' size='340' side='right'caption='[[4nap]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nap]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Desdg Desdg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NAP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nap]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oleidesulfovibrio_alaskensis_G20 Oleidesulfovibrio alaskensis G20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nap OCA], [https://pdbe.org/4nap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nap RCSB], [https://www.ebi.ac.uk/pdbsum/4nap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nap ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dde_0634 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=207559 DESDG])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nap OCA], [http://pdbe.org/4nap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nap RCSB], [http://www.ebi.ac.uk/pdbsum/4nap PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nap ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DCTP2_OLEA2 DCTP2_OLEA2] Solute-binding protein that binds indole-3-pyruvate and indole-3-acetate (in vitro). Can also bind D-tryptophan (in vitro), but that is probably not a physiological ligand (PubMed:25540822). Probably part of a tripartite ATP-independent periplasmic (TRAP) transport system that mediates solute transport into the cytoplasm.<ref>PMID:25540822</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Desdg]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Oleidesulfovibrio alaskensis G20]]
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[[Category: Attonito, J D]]
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[[Category: Al Obaidi NF]]
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[[Category: Chowdhury, S]]
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[[Category: Almo SC]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Attonito JD]]
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[[Category: Evans, B]]
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[[Category: Chowdhury S]]
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[[Category: Gerlt, J A]]
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[[Category: Evans B]]
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[[Category: Glenn, A Scott]]
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[[Category: Gerlt JA]]
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[[Category: Hillerich, B]]
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[[Category: Hillerich B]]
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[[Category: Imker, H J]]
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[[Category: Imker HJ]]
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[[Category: Love, J]]
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[[Category: Love J]]
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[[Category: Morisco, L L]]
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[[Category: Morisco LL]]
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[[Category: Obaidi, N F.Al]]
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[[Category: Scott Glenn A]]
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[[Category: Seidel, R D]]
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[[Category: Seidel RD]]
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[[Category: Sojitra, S]]
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[[Category: Sojitra S]]
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[[Category: Stead, M]]
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[[Category: Stead M]]
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[[Category: Vetting, M W]]
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[[Category: Vetting MW]]
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[[Category: Wasserman, S R]]
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[[Category: Wasserman SR]]
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[[Category: Efi]]
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[[Category: Enzyme function initiative]]
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[[Category: Structural genomic]]
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[[Category: Transport protein]]
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[[Category: Trap periplasmic solute binding family]]
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Current revision

Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan

PDB ID 4nap

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